Rockville, USA, October 4–7, 2021
Scientific Program
Download Schedule at-a-glance (PDF)
Monday, October 4, 2021
7 a.m. Welcoming Remarks
Michelle Gumz, PhD, University of Florida
Kelly Hyndman, PhD, University of Alabama at Birmingham
7:05–8 a.m. Opening Lecture “ERA lipids CKD”
Neeraj "Bean" Dhaun, Royal Infirmary of Edinburgh, Scotland, MD, PhD
8–8:30 a.m. Break
8:30–10 a.m. Session 1
Renal Physiology and Diseases
Chairs:
Ivana Vaněčková, PhD, The Czech Academy of Sciences, Czech Republic;
Jermaine Johnston, PhD, University of Florida
8:30–9 a.m. “Why aprocitentan in resistant hypertension?”
Martine Clozel, MD, Idorsia Pharmaceuticals, Switzerland
9–9:15 a.m. Talk selected from submitted abstracts TBD
9:15–9:30 a.m. Talk selected from submitted abstracts TBD
9:30–10 a.m. “ETA receptors for degradation of the glomerular endothelial surface layer via pathologic cross-talk between activated podocytes and glomerular endothelial cells”
Ilse Daehn, PhD, Icahn School of Medicine at Mount Sinai, New York
10–10:30 a.m. Breakout room chats
10:30 a.m.–12:30 p.m. Session 2
Cardiovascular Physiology and Diseases
Chairs:
David Webb, MD, DSc, The Queen's Medical Research Institute, Scotland
Carmen De Miguel, PhD, University of Alabama at Birmingham
10:30–11 a.m. “ETB postmenopause”
Megan Wenner, PhD, University of Delaware
11–11:15 a.m. Talk selected from submitted abstracts TBD
11:15–11:30 a.m. Talk selected from submitted abstracts TBD
11:30–11:45 a.m. Talk selected from submitted abstracts TBD
11:45 a.m.–12:15 p.m. “Adipose tissue ET-1 in obesity and insulin resistance”
Joshua Speed, PhD, University of Mississippi Medical Center
12:15–12:30 p.m. Talk selected from submitted abstracts TBD
Tuesday, October 5, 2021
7 a.m. Welcome
Michelle Gumz, PhD, University of Florida
Kelly Hyndman, PhD, University of Alabama at Birmingham
7:05–8:50 a.m. Session 3
Recent Advances in Cancer
Chairs:
Anil Gulati, MD, PhD Pharmazz, Inc., Willowbrook, Illinois
Piera Tocci, PhD, Italian Ministry of Health, Italy
7:05–8:50 a.m.
7:05–7:35 a.m. “Ambrisentan in cancer mets”
Otavio Cabral-Marques, PhD, University of São Paulo, Brazil
7:35–7:50 a.m. Talk selected from submitted abstracts TBD
7:50–8:05 a.m. Talk selected from submitted abstracts TBD
8:05–8:35 a.m. “ET and YAP alliance in cancer”
Anna Bagnato, PhD, Regina Elena National Cancer Institute, Italy
8:35–8:50 a.m. Talk selected from submitted abstracts TBD
8:50–9:30 a.m. Breakout room chats
9:30–10:30 a.m. Poster session 1
10:30 a.m.–12 p.m. Session 4
Neurophysiology and Neurological Disorders
Chairs:
Rita Tostes, PhD, University of São Paulo, Brazil
Bryan Becker, PhD, University of Alabama at Birmingham
10:30–11 a.m. “Capillary pericyte contraction by Aβ-evoked ET-1 release as a therapeutic target for Alzheimer's disease”
Nils Korte, PhD, University College London, U.K.
11–11:15 a.m. Talk selected from submitted abstracts TBD
11:15– 11:30 a.m. Talk selected from submitted abstracts TBD
11:30 a.m.–12 p.m. “The endothelin system in neurovascular function: lessons learned in diabetes”
Adyvie Ergul, MD, PhD, Medical College of Charleston
Wednesday, October 6, 2021
7 a.m. Welcome
Michelle Gumz, PhD, University of Florida
Kelly Hyndman, PhD, University of Alabama at Birmingham
7:05–8:50 a.m. Session 5
Hot Topics in ET Research
Chairs:
Ernesto Schiffrin, MD, PhD, McGill University, Canada
Megan Rhoads, PhD, University of Alabama at Birmingham
7:05–7:35 a.m. “Blood- brain barrier”
Shotaro Michinaga, PhD, Osaka Ohtani University, Japan
7:35–7:50 a.m. Talk selected from submitted abstracts TBD
7:50–8:05 a.m. Talk selected from submitted abstracts TBD
8:05–8:20 a.m. Talk selected from submitted abstracts TBD
8:20–8:50 a.m. “Gut microbiome and ET system”
Craig Maynard, PhD, University of Alabama at Birmingham
8:50–9:30 a.m. Breakout room chats
9:30–10:30 a.m. Poster session 2
10:30 a.m.–12 p.m. Session 6
ERAs in Clinical Trials
Chairs:
Anthony Davenport, PhD, University of Cambridge, U.K.
Lauren Douma, PhD, University of Florida
10:30–11 a.m. “Update on SONAR”
Don Kohan, MD, PhD, FAPS, University of Utah
11–11:30 a.m. “Study of sparsentan in patients with primary focal segmental glomerulosclerosis (FSGS) (DUPLEX)”
Radko Komers, MD, PhD, Travere Therapeutics, Inc., San Diego
11:30 a.m.–12 p.m. “Atrasentan in patients with IgA nephropathy (ALIGN)”
Alain Romero, PhD, PharmD, Chinook Therapeutics U.S., Inc., Seattle
12–12:30 p.m. “PRIZE study, repurposing zibotentan in microvascular angina”
Andrew Morrow, MBChB, University of Glasgow, Scotland
Thursday, October 7, 2021
7 a.m. Welcome
Michelle Gumz, PhD, University of Florida
Kelly Hyndman, PhD, University of Alabama at Birmingham
7:05–8 a.m. Professional Networking Session
Virtual coffee with experts
Breakout rooms with trainees and the ET International Advisory Board
8–9:15 a.m. Session 7
Other Organ Systems
Chairs:
John Pernow, PhD, Karolinska Institute, Sweden
Janet Maguire, PhD, University of Cambridge, U.K.
8–8:30 a.m. Invited talk
Speaker: TBA
8:30–8:45 a.m. Talk selected from submitted abstracts TBD
8:45–9 a.m. Talk selected from submitted abstracts TBD
9–9:15 a.m. Talk selected from submitted abstracts TBD
9:15–9:45 a.m. Break
9:45–10:15 a.m. “Q&A with Masashi Yanagisawa: thoughts on the field”
Masashi Yanagisawa, MD, PhD, University of Tsukuba, Japan
Chairs:
Michelle Gumz, PhD, University of Florida
Kelly Hyndman, PhD, University of Alabama at Birmingham
10:15–10:30 a.m. Memorial for Tomoh Masaki, MD, PhD
Masashi Yanagisawa, MD, PhD, University of Tsukuba, Japan
10:30–11 a.m. Award announcements and passing of the ET-17 gavel
Closing remarks
Michelle Gumz, PhD, University of Florida;
Kelly Hyndman, PhD, University of Alabama at Birmingham
Table of Sessions
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